Recombinant Human BAG2 (N-6His)

Description

EnkiLife provides the Recombinant Human BAG2 (N-6His) protein,aslo know as BAG Family Molecular Chaperone Regulator 2,BAG-2,Bcl-2-Associated Athanogene 2,BAG2, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human BAG Family Molecular Chaperone Regulator 2 is produced by our E.coli expression system and the target gene encoding Met1-Asn211 is expressed with a 6His tag at the N-terminus.Accession:O95816. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:25.9 KDa. Background:BAG Family Molecular Chaperone Regulator 2 (BAG2) is a member of the Bag family whose members compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. BAG2 contains 1 BAG domain and is a important component of the HSC 70/CHIP chaperone-dependent ubiquitin ligase complex. In mammalian cells BAG1, BAG2, and BAG3 bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.