Recombinant Human BCAS2 (C-6His, N-T7 tag)

Description

EnkiLife provides the Recombinant Human BCAS2 (C-6His, N-T7 tag) protein,aslo know as Pre-mRNA-Splicing Factor SPF27,Breast Carcinoma-Amplified Sequence 2,DNA Amplified in Mammary Carcinoma 1 Protein,Spliceosome-Associated Protein SPF 27,BCAS2,DAM1, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Breast Carcinoma-Amplified Sequence 2 is produced by our E.coli expression system and the target gene encoding Ala2-Phe225 is expressed with a T7 tag at the N-terminus, 6His tag at the C-terminus.Accession:O75934. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:28.58 KDa. Background:Breast Carcinoma-Amplified Sequence 2 (BCAS2) is a member of the SPF27 family. BCAS2 is a nuclear protein and widely expressed in many rtissues. BCAS2 is identified as being overexpressed in various breast cancer cell lines. BCAS2 is a component of the spliceosome, taking part in the removal of introns from mRNA precursors. BCAS2 interacts with estrogen receptor alpha and beta, thyroid hormone receptor beta, peroxisome proliferator-activated receptor gamma. BCAS2 functions as an ER co-activator and is capable of enhancing ER-mediated transcription.