Recombinant Human BCMA (C-Fc)

Description

EnkiLife provides the Recombinant Human BCMA (C-Fc) protein,aslo know as Tumor necrosis factor receptor superfamily member 17;TNFRSF17;B-cell maturation protein;CD269, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human B-cell Maturation Protein is produced by our Mammalian expression system and the target gene encoding Met1-Ala54 is expressed with a human IgG1 Fc tag at the C-terminus.Accession:Q02223. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:32.8 KDa. Background:B cell maturation protein (BCMA) is a type III membrane protein which belongs to the TNF receptor superfamily (TNFRSF17). BCMA contains one extracellular cysteine rich domain, as well as TACI. Human BCMA is a 184 amino acid (aa) protein consisting of a 54 aa extracellular domain, a 23 aa transmembrane domain, and a 107 aa intracellular domain. Mouse and human BCMA share 62% amino acid identity. BCMA is mainly expressed in immune organs and mature B cell lines. BCMA appears to be localized to the Golgi compartment. BCMA may play an important role in B cell development, function and regulation.