Recombinant Human BMP-4

Description

EnkiLife provides the Recombinant Human BMP-4 protein,aslo know as Bone morphogenetic protein 4,BMP-4,BMP4,BMP2B,DVR4, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<0.01 EU/µg as determined by LAL test.;Construction:Recombinant Human Bone morphogenetic protein 4 is produced by our E.coli expression system and the target gene encoding Ser293-Arg408.Accession:P12644. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:13.3 KDa. Background:Bone morphogenic protein-4 (BMP-4) is one of nine structurally related BMPs belonging to the transforming growth factor-beta (TGF-beta) superfamily of secreted proteins. Mature BMP-4 is a dimer that binds to a multimeric transmembrane receptor with serine/threonine kinase activity. BMP-4 has important roles as a signalling molecule in embryonic tissues, including the developing central and peripheral nervous system, musculature and skeleton. BMP-4 as well as its receptors and their signal transduction pathways play a crucial role in the control of the differentiation and proliferation of the different cell types that constitute the anterior pituitary.