Recombinant Human BMP-7

Description

EnkiLife provides the Recombinant Human BMP-7 protein,aslo know as Bone morphogenetic protein 7,BMP-7,Osteogenic protein 1 (OP-1),Eptotermin alfa,BMP7,OP1, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Bone morphogenetic protein 7 is produced by our Mammalian expression system and the target gene encoding Ser293-His431 is expressed.Accession:P18075. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:15.5 KDa. Background:Bone morphogenetic protein 7 (BMP7), also known as osteogenic protein-1 (OP-1) is a member of Transforming growth factor-β (TGF-β) family of proteins. Bone morphogenetic proteins were discovered in 1965 by Marshal Urist, of which BMP7 is of particular interest in this review being a leptin-independent anorexinogen and having role in energy expenditure in the brown adipose tissue, which makes it a potential target for preventing/treating obesity. As it has been established that Obesity displays a state of leptin-resistance, thus a protein-like BMP7 which acts through a leptin-independent pathway could give new therapeutic directions.