Recombinant Human Calmegin (C-6His)

Description

EnkiLife provides the Recombinant Human Calmegin (C-6His) protein,aslo know as Calmegin,CLGN, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Calmegin is produced by our Mammalian expression system and the target gene encoding Glu20-Trp471 is expressed with a 6His tag at the C-terminus.Accession:O14967. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:52.9 KDa. Background:Calmegin (CLGN) is a member of the calreticulin family. Calmegin is a testis-specific endoplasmic reticulum chaperone protein. The functions during spermatogenesis as a chaperone for a range of client proteins that is important for sperm adhesion onto the egg zona pellucida and for subsequent penetration of the zona pellucida. It is required for normal male fertility, normal sperm migration from the uterus into the oviduct. Calmegin binds calcium ions and interacts with PDILT. Calmegin may play a role in spermatogeneisis and infertility.