Recombinant Human Carbonic Anhydrase 1 (C-6His)

Description

EnkiLife provides the Recombinant Human Carbonic Anhydrase 1 (C-6His) protein,aslo know as Carbonic Anhydrase 1,Carbonate Dehydratase I,Carbonic Anhydrase B,CAB,Carbonic Anhydrase I,CA-I,CA1, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Carbonic Anhydrase 1 is produced by our E.coli expression system and the target gene encoding Ala2-Phe261 is expressed with a 6His tag at the C-terminus.Accession:P00915. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:29.93 KDa. Background:Carbonic Anhydrase 1 (CA1) is a cytosolic enzyme, belonging to the alpha-carbonic anhydrase family. It is highly expressed in erythrocytes and acts as an early marker for erythroid differentiation. Carbonic anhydrase 1 plays a improtant role in many biological processes such as calcification, cellular respiration, bone resorption, acid-base balance. It is activated by imidazole, histamine, L-adrenaline, L- and D-histidine, and L- and D-phenylalanine. At the same time, It is inhibited by sulfonamide derivatives and coumarins. In addition, CA1 is a zinc metalloenzyme that has reversible hydration of carbon dioxide. It can hydrate cyanamide to urea.