Recombinant Human Carbonic Anhydrase 5B (C-6His)

Description

EnkiLife provides the Recombinant Human Carbonic Anhydrase 5B (C-6His) protein,aslo know as Carbonic Anhydrase 5B Mitochondrial,Carbonate Dehydratase VB,Carbonic Anhydrase VB,CA-VB,CA5B, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Carbonic Anhydrase 5B is produced by our E.coli expression system and the target gene encoding Cys34-Pro317 is expressed with a 6His tag at the C-terminus.Accession:Q9Y2D0. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:33.77 KDa. Background:Carbonic Anhydrase 5B (CA5B) is a member of alpha-carbonic anhydrase family (CAs) that catalyze the reversible hydration of carbon dioxide. CAs is associated with many biological processes, including calcification, respiration, bone resorption, acid-base balance and the formation of aqueous humor. CA5B is highly expressed in heart, pancreas, kidney, placenta, lung, and skeletal muscle, but it is restricted to the liver. CA5B is localized in the mitochondria and shows the highest sequence similarity to the other mitochondrial CA, CA-VA. CA5B is inhibited by coumarins, sulfonamide derivatives such as acetazolamide (AZA), saccharin, and Foscarnet.