Recombinant Human CCL17 (C-6His)

Description

EnkiLife provides the Recombinant Human CCL17 (C-6His) protein,aslo know as ABCD-2,CC chemokine TARC,C-C motif chemokine 17,CCL17,chemokine (C-C motif) ligand 17,MGC138273,SCYA17MGC138271,small inducible cytokine subfamily A (Cys-Cys), member 17,Small-inducible cytokine A17,T cell-directed CC chemokine,TARC,TARCA-152E5.3,Thymus and activation-regulated chemokine, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human C-C Motif Chemokine 17 is produced by our Mammalian expression system and the target gene encoding Ala24-Ser94 is expressed with a 6His tag at the C-terminus.Accession:Q92583. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:9.1 KDa. Background:C-C motif chemokine 17 (CCL17) is a novel CC chemokine, it belongs to the intercrine beta (chemokine CC) family. CCL17 is expressed at high levels in thymus, and at a lower level in lung, colon, and small intestine. CCL17 is also transiently expressed in stimulated peripheral blood mononuclear cells. Among CC chemokine family members, CCL17 has approximately 24 - 29% amino acid sequence identity with RANTES, MIP-1 alpha, MIP-1 beta, MCP-1, MCP-2 and MCP-3. CCL17 has been identified to be Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. CCL17 plays a role in T-cell development in thymus and in trafficking and activation of mature T-cells.