Recombinant Human CCL18 (N-6His)

Description

EnkiLife provides the Recombinant Human CCL18 (N-6His) protein,aslo know as C-C Motif Chemokine 18,Alternative Macrophage Activation-Associated CC Chemokine 1,AMAC-1,CC Chemokine PARC,Dendritic Cell Chemokine 1,DC-CK1,Macrophage Inflammatory Protein 4,MIP-4,Pulmonary and Activation-Regulated Chemokine,Small-Inducible Cytokine A18,CCL18,AMAC1,DCCK1,MIP4,PARC,SCYA18, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human C-C Motif Chemokine 18 is produced by our E.coli expression system and the target gene encoding Ala21-Ala89 is expressed with a 6His tag at the N-terminus.Accession:P55774. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:10.1 KDa. Background:C-C Motif Chemokine 18 (CCL18) is secreted protein that belongs to the intercrine beta (chemokine CC) family. CCL18 is expressed at high levels in the lung, lymph nodes, placenta, bone marrow, and dendritic cells. CCL18 is a chemotactic factor that attracts lymphocytes but not monocytes or granulocytes. CCL18 may be involved in B-cell migration into B-cell follicles in lymph nodes. CCL18 attracts naive T-lymphocytes toward dendritic cells and activated macrophages in lymph nodes. It has chemotactic activity for naive T-cells, CD4+ and CD8+ T-cells and thus may play a role in both humoral and cell-mediated immunity responses.