Recombinant Human CCL8

Description

EnkiLife provides the Recombinant Human CCL8 protein,aslo know as C-C Motif Chemokine 8,HC14,Monocyte Chemoattractant Protein 2,Monocyte Chemotactic Protein 2,MCP-2,Small-Inducible Cytokine A8,CCL8,MCP2,SCYA10,SCYA8, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human C-C Motif Chemokine 8 is produced by our E.coli expression system and the target gene encoding Gln24-Pro99 is expressed.Accession:P80075. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:8.9 KDa. Background:Human Chemokine (C-C Motif) Ligand 8 (CCL8) is produced by human MG63 osteosarcoma cells. CCL8 shares 62% and 58% amino acid sequence identity with MCP-1 and MCP-3, respectively. All three MCP proteins are monocyte chemoattractants. CCL8 is chemotactic for and activates many different immune cells, including mast cells, eosinophils and basophils, which are implicated in allergic response, and monocytes, T cells, and NK cells that are involved in the inflammatory response. CCL8 elicits its effects by binding to several different cell surface receptors including CCR1, CCR2B and CCR5.