Recombinant Human CD200 R1 (C-6His)

Description

EnkiLife provides the Recombinant Human CD200 R1 (C-6His) protein,aslo know as Cell Surface Glycoprotein CD200 Receptor 1,CD200 Cell Surface Glycoprotein Receptor,Cell Surface Glycoprotein OX2 Receptor 1,CD200R1,CD200R,CRTR2,MOX2R,OX2R, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human CD200 Receptor 1 is produced by our Mammalian expression system and the target gene encoding Ala27-Leu266 is expressed with a 6His tag at the C-terminus.Accession:AAH69721.1. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:27.82 KDa. Background:Cell surface glycoprotein CD200 Receptor 1 (CD200R1) is the receptor for the CD200 (OX-2) membrane glycoprotein. CD200R1 contains one C2- type Ig-like domain and one V-type Ig-like domain within its extracellular domain and a PTB-signaling motif in cytoplasmic domain. CD200R1 and CD200 associate via their respective N-terminal Ig-like domains. CD200R1 is restricted primarily to mast cells, basophils, macrophages, and dendritic cells. It propagates inhibitory signals despite its lacking a cytoplasmic ITIM (immunoreceptor tyrosinebased inhibitory motif). The receptor-substrate interaction may function as a myeloid downregulatory signal.