Recombinant Human CD27 (C-Fc-6His)

Description

EnkiLife provides the Recombinant Human CD27 (C-Fc-6His) protein,aslo know as CD27 antigen;CD27L receptor,T-cell activation antigen CD27,Tumor necrosis factor receptor superfamily member 7,T14 and TNFRSF7., which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human CD27 is produced by our Mammalian expression system and the target gene encoding Thr21-Ile192 is expressed with a human IgG1 Fc, 6His tag at the C-terminus.Accession:P26842. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:47.2 KDa. Background:CD27 antigen is also known as CD27L receptor, T-cell activation antigen CD27, Tumor necrosis factor receptor superfamily member 7, T14 and TNFRSF7. In humans, it is encoded by the CD27 gene. CD27 is a single-pass type I membrane protein with 3 TNFR-Cys repeats. It is a member of the TNF-receptor superfamily and is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. It plays a role in survival of activated T-cells and apoptosis through association with SIVA1.