Recombinant Human CD27L (C-mFc)

Description

EnkiLife provides the Recombinant Human CD27L (C-mFc) protein,aslo know as CD70 antigen,CD70,CD27 ligand,Tumor necrosis factor ligand superfamily member 7,CD27LG,TNFSF7,CD27L, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human CD27 Ligand/CD70 is produced by our Mammalian expression system and the target gene encoding Gln45-Pro193 is expressed with a mouse IgG1 Fc tag at the C-terminus.Accession:P32970. Expression Host:Human Cells.Species:Human .Predicted Molecular Mass:43 KDa. Background:CD27 Ligand (CD70) is a 30 kDa type 2 transmembrane glycoproteinis that belongs to the tumor necrosis factor (TNF) ligand family.Human CD27 Ligand extracellular region is 64% aa identical to mouse and rat CD27 Ligand extracellular regions. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.