Recombinant Human CD300a (C-6His)

Description

EnkiLife provides the Recombinant Human CD300a (C-6His) protein,aslo know as CMRF35-Like Molecule 8,CLM-8,CD300 Antigen-Like Family Member A,CMRF-35-H9,CMRF35-H9,CMRF35-H,IRC1/IRC2,Immunoglobulin Superfamily Member 12,IgSF12,Inhibitory Receptor Protein 60,IRp60,NK Inhibitory Receptor,CD300a,CD300A,CMRF35H,IGSF12, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Leukocyte Mono-Ig-like Receptor 1 is produced by our Mammalian expression system and the target gene encoding Leu18-Gln178 is expressed with a 6His tag at the C-terminus.Accession:Q9UGN4. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:18.48 KDa. Background:CD300A is a single-pass type I membrane protein that belongs to the CD300 family. CD300A consists of a 163 amino acid (aa) extracellular domain (ECD) with one Ig-like V- type domain, a 21 amino acid transmembrane segment, and a 98 amino acid cytoplasmic domain with tyrosine residues. CD300A is expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes. CD300A is an inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation.