Recombinant Human CD38 (C-mFc)

Description

EnkiLife provides the Recombinant Human CD38 (C-mFc) protein,aslo know as ADP-ribosyl cyclase 1,cyclic ADP-ribose hydrolase;CD38;T10, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human ADP-ribosyl Cyclase/cyclic ADP-ribose Hydrolase 1 is produced by our Mammalian expression system and the target gene encoding Val43-Ile300 is expressed with a mouse IgG1 Fc tag at the C-terminus.Accession:P28907. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:56.5 KDa. Background:CD38, also called ADP-ribosyl cyclase, is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. And also moonlights as a receptor in cells of the immune system. CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells. Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic beta cells.