Recombinant Human CD64 (C-6His)

Description

EnkiLife provides the Recombinant Human CD64 (C-6His) protein,aslo know as High affinity immunoglobulin gamma Fc receptor I,IgG Fc receptor I,Fc-gamma RI,FcRI,Fc-gamma RIA,FcgammaRIa,CD64,FCGR1A, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human High Affinity Immunoglobulin Gamma Fc Receptor I is produced by our Mammalian expression system and the target gene encoding Gln16-Pro288 is expressed with a 6His tag at the C-terminus.Accession:P12314. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:31.7 KDa. Background:CD64 (FcγRI), one of the Fc receptors for IgG, is a membrane glycoprotein that mediates endocytosis, phagocytosis, antibody-dependent cellular cytotoxicity, cytokine release, and superoxide production. CD64 is also structurally distinct, containing an extracellular Ig-interactive region of three Ig-like domains in contrast to the two domains of the low affinity receptors FcγRII and FcγRIII. It is normally expressed on the surfaces of monocytes and macrophages.