Recombinant Human CD79A(C-6His)

Description

EnkiLife provides the Recombinant Human CD79A(C-6His) protein,aslo know as CD79A antigen,CD79a antigen,CD79A,MB1,MB-1, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human CD79A is produced by our Mammalian expression system and the target gene encoding Leu33-Arg143 is expressed with a 6His tag at the C-terminus.Accession:P11912. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:13.4 KDa. Background:CD79A (also known as Mb-1, Ig alpha and B cell antigen receptor complex-associated protein alpha-chain) is a 30-40 kDa member of the Ig-Superfamily. Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.