Recombinant Human CD81 (N-FC)

Description

EnkiLife provides the Recombinant Human CD81 (N-FC) protein,aslo know as CD81 antigen,CD81 molecule,CD81,CVID6,TAPA1,TAPA-1,TSPAN28, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human CD81 antigen is produced by our Mammalian expression system and the target gene encoding Phe113-Lys201 is expressed with a human IgG1 Fc tag at the N-terminus.Accession:P60033. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:36.1 KDa. Background:CD81, also known as TAPA-1 and Tetraspanin-28, belongs to the transmembrane 4 superfamily, also known as the tetraspanin family. Members of this family mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD81 is a widely expressed cell-surface protein involved in an astonishing variety of biologic responses. CD81 associates with a wide range of membrane proteins including CD151, TfR2, LDL R, PCSK9, Glypican 3, IFITM1, IGSF8/CD316, FPRP, and complexes of CD19-CD21. It is related to adhesion, morphology, activation, proliferation, and differentiation of B, T, and other cells. CD81 additionally functions as a receptor for the E2 glycoprotein of hepatitis C virus. The CD81-E2 interaction inhibits NK cell cytolytic activity, provides a co-stimulatory signal to T cells, and inhibits the maturation of plasmacytoid dendritic cells.