Recombinant Human CDH11 (C-6His)

Description

EnkiLife provides the Recombinant Human CDH11 (C-6His) protein,aslo know as Cadherin 11 Type 2 OB-cadherin (Osteoblast),Cadherin 11 Type 2 OB-Cadherin (Osteoblast) Isoform CRA_c,CDH11, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Cadherin-11 is produced by our Mammalian expression system and the target gene encoding Phe23-Thr617 is expressed with a 6His tag at the C-terminus.Accession:Q96CZ9. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:66.63 KDa. Background:Cadherin-11 is a type II classical cadherin member of the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Cadherins interact with themselves in a homophilic manner in connecting cells, and thus contribute to the sorting of heterogeneous cell types. Cadherin-11 contains five cadherin domains and is mainly expressed in the brain. Mature cadherin proteins consists of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small highly conserved C-terminal cytoplasmic domain. It is shown that Cadherin-11 is a viable molecular target for therapeutic intervention in Glioblastoma multiforme.