Recombinant Human CEACAM8 (C-6His)

Description

EnkiLife provides the Recombinant Human CEACAM8 (C-6His) protein,aslo know as Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8,CD67 Antigen,Carcinoembryonic Antigen CGM6,Non-Specific Cross-Reacting Antigen NCA-95,CD66b,CEACAM8,CGM6, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8 is produced by our Mammalian expression system and the target gene encoding Gln35-His141 is expressed with a 6His tag at the C-terminus.Accession:P31997. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:13.03 KDa. Background:Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8 (CEACAM8) is a single chain, GPI-anchored, highly glycosylated protein which belongs to the immunoglobulin superfamily and the carcinoembryonic antigen(CEA) family. CEACAM8 is expressed by neutrophils and eosinophils, and serves as a binding partner for CEACAM-6 and Galectin-3. It contains two Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. Mature human CEACAM8 is a 287 amino acid GPI-linked glycoprotein. CEACAM family members are a set of widely expressed proteins involved in several biological functions, including cell adhesion, migration, signal transduction, and the regulation of gene expression. Abnormal overexpression and downregulation of some CEACAMs have been described in tumor cells.