Recombinant Human CGREF1 (C-6His)

Description

EnkiLife provides the Recombinant Human CGREF1 (C-6His) protein,aslo know as Cell Growth Regulator with EF Hand Domain Protein 1,Cell Growth Regulatory Gene 11 Protein,Hydrophobestin,CGREF1,CGR11, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Cell Growth Regulator With EF Hand Domain Protein 1 is produced by our Mammalian expression system and the target gene encoding Ala20-Ile301 is expressed with a 6His tag at the C-terminus.Accession:A0A4W8VYG7. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:30.9 KDa. Background:Cell Growth Regulator with EF Hand Domain Protein 1 (CGREF1) is a secreted calcium ion binding protein. CGREF1 contains two EF-hand domains and both EF-hands are required for function. Human CGREF1 is synthesized as a 301 amino acid precursor that contains a 19 amino acid signal sequence, and a 282 amino acid mature chain. CGREF1 is probably digested extracellularly by an unknown serine protease generating extremely hydrophobic bioactive peptides. CGREF1 mediates cell-cell adhesion in a calcium-dependent manner. In addition, CGREF1 is able to inhibit growth in several cell lines.