Recombinant Human CLEC3B (C-6His)

Description

EnkiLife provides the Recombinant Human CLEC3B (C-6His) protein,aslo know as Tetranectin,TN,C-Type Lectin Domain Family 3 Member B,Plasminogen Kringle 4-Binding Protein,CLEC3B,TNA, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human C-Type Lectin Domain Family 3 Member B is produced by our Mammalian expression system and the target gene encoding Glu22-Val202 is expressed with a 6His tag at the C-terminus.Accession:AAH11024.1. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:21.21 KDa. Background:C-Type Lectin Domain Family 3 Member B (CLEC3B) is a serum and tissue protein and it contais a C-type lectin which binds to Ca++. CLEC3B is originally found in plasma, the concentrations approximately 10mg/l. It can bind to kringle 4 of plasminogen and enhance the activation of plaminogen to plasmin, catalyzed by tissue plasminogen activator in the presence of poly-D-lysine. In addition, CLEC3B may be involved in the packaging of molecules destined for exocytosis. Also, CLEC3B is best known as a prognostic marker in ovarian cancer.