Recombinant Human CNDP1 (C-6His)

Description

EnkiLife provides the Recombinant Human CNDP1 (C-6His) protein,aslo know as Beta-Ala-His Dipeptidase,CNDP Dipeptidase 1,Carnosine Dipeptidase 1,Glutamate Carboxypeptidase-Like Protein 2,Serum Carnosinase,CNDP1,CN1,CPGL2, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Carnosine Dipeptidase 1 is produced by our Mammalian expression system and the target gene encoding Ser27-His507 is expressed with a 6His tag at the C-terminus.Accession:AAI13513.1. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:54.9 KDa. Background:Carnosine Dipeptidase 1 (CNDP1) belongs to the M20 metalloprotease family. CNDP1 is specifically expressed in the brain, serum and adult nervous central system. It is identified as human carnosinase. CNDP1 contains trinucleotide (CTG) repeat length polymorphism in the coding region and is inhibited by the metal chelator 1,10-o-phenantrolin. In addition, CNDP1 can hydrolyse the beta-Ala|-His dipeptide (carnosine), anserine, Xaa-|-His dipeptides and other dipeptides including homocarnosine. CNDP1 deficiency has been associated with homocarnosinosis disease.