Recombinant Human CRADD

Description

EnkiLife provides the Recombinant Human CRADD protein,aslo know as Death Domain-Containing Protein CRADD,Caspase and RIP Adapter with Death Domain,RIP-Associated Protein with A Death Domain,CRADD,RAIDD, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Caspase and RIP Adapter With Death Domain is produced by our E.coli expression system and the target gene encoding Met1-Glu199 is expressed.Accession:P78560. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:23 KDa. Background:Death Domain-Containing Protein CRADD (CRADD) is widely expressed in most tissues, with particularly high expression in the adult heart, testis, liver, skeletal muscle, fetal liver, and kidney. CRADD contains one CARD domain that mediates the interaction with caspase-2, and one death domain involved in the binding of RIP protein. CRADD functions as an apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. CRADD induces cell apoptosis/cell death in numerous tissues. Defects in CRADD will result in mental retardation.