Recombinant Human CRYAB (C-6His)

Description

EnkiLife provides the Recombinant Human CRYAB (C-6His) protein,aslo know as Alpha-Crystallin B Chain,Alpha(B)-Crystallin,Heat Shock Protein Beta-5,HspB5,Renal Carcinoma Antigen NY-REN-27,Rosenthal Fiber Component,CRYAB,CRYA2, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Crystalline Alpha -B Chain is produced by our E.coli expression system and the target gene encoding Met1-Lys175 is expressed with a 6His tag at the C-terminus.Accession:P02511. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:21.22 KDa. Background:α Crystallin B Chain (CRYAB) is a cytoplasmic protein that belongs to the small heat shock protein (HSP20) family. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20) family. Alpha crystallins acts as molecular chaperones and hold them in in large soluble aggregates. CRYAB is expressed widely in many tissues and organs. It may contribute to the transparency and refractive index of the lens. The deficiency of CRYAB is the cause of myopathy myofibrillar type 2 (MFM2) and cataract posterior polar type 2 (CTPP2).