Recombinant Human CSF2RA (C-6His)

Description

EnkiLife provides the Recombinant Human CSF2RA (C-6His) protein,aslo know as Granulocyte-Macrophage Colony-Stimulating Factor Receptor Subunit Alpha,GM-CSF-R-Alpha,GMCSFR-Alpha,GMR-Alpha,CDw116,CD116,CSF2RA,CSF2R,CSF2RY, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor Receptor Subunit Alhpa is produced by our Mammalian expression system and the target gene encoding Glu23-Gly320 is expressed with a 6His tag at the C-terminus.Accession:P15509. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:35.5 KDa. Background:Granulocyte-Macrophage Colony-Stimulating Factor Receptor Subunit α (CSF2RA) is a single-pass type I membrane protein which belongs to the type I cytokine receptor family of Type 5 subfamily. The CSF2RA gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes with some of the isoforms being membrane-bound and others being soluble. CSF2RA is a low affinity receptor for granulocyte-macrophage colony-stimulating factor. CSF2RA transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells. Defects in CSF2RA are the cause of pulmonary surfactant metabolism dysfunction type 4 (SMDP4).