Recombinant Human CTGF (C-6His)

Description

EnkiLife provides the Recombinant Human CTGF (C-6His) protein,aslo know as Connective tissue growth factor,CTGF, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Connective Tissue Growth Factor is produced by our Mammalian expression system and the target gene encoding Gln27-Ala349 is expressed with a 6His tag at the C-terminus.Accession:Q5M8T4. Expression Host:Human cells.Species:Human.Predicted Molecular Mass:36.3 KDa. Background:Connective Tissue Growth Factor (CTGF), also known as CCN2, is a member of the CCN (CYR61/CTGF/NOV) family of secreted matricellular proteins. Like other CCN proteins, mature human CTGF consists of IGF-binding protein domain, a vWF-C domain, a TSP-1 domain, and a cysteine knot heparin-binding domain. CTGF has various biological functions, including cell adhesion, migration, proliferation, differentiation, and ECM production, and participates in the development of many organs under normal physiologic conditions. CTGF is pathologically viewed as a central mediator of tissue remodeling and fibrosis of various organs, including the lung, heart, liver, and kidney.