Recombinant Human CTH

Description

EnkiLife provides the Recombinant Human CTH protein,aslo know as Cystathionine Gamma-Lyase,Cysteine-Protein Sulfhydrase,Gamma-Cystathionase,CTH, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Cystathionine Gamma-Lyase is produced by our E.coli expression system and the target gene encoding Met1-Ser405 is expressed.Accession:P32929. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:44.7 KDa. Background:Cystathionine Gamma-Lyase (CTH) belongs to the trans-sulfuration enzymes family. CTH exists as a homotetramer and interacts with CALM in a calcium-dependent manner. CTH breaks down cystathionine into cysteine, ammonia and 2-oxobutanoate. CTH catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine and has broad substrate specificity. Defects in CTH will lead to cystathioninuria, which is an autosomal recessive phenotype characterized by abnormal accumulation of plasma cystathionine.