Recombinant Human CXCL1 (C-6His)

Description

EnkiLife provides the Recombinant Human CXCL1 (C-6His) protein,aslo know as Growth-Regulated Alpha Protein,C-X-C Motif Chemokine 1,GRO-Alpha(1-73),Melanoma Growth Stimulatory Activity,MGSA,Neutrophil-Activating Protein 3,NAP-3,CXCL1,GRO,GRO1,GROA,MGSA,SCYB1, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<0.01 EU/µg as determined by LAL test.;Construction:Recombinant Human C-X-C Motif Chemokine 1 is produced by our Mammalian expression system and the target gene encoding Ala35-Asn107 is expressed with a 6His tag at the C-terminus.Accession:P09341. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:8.9 KDa. Background:Chemokine (C-X-C motif) Ligand 1 Protein (CXCL1) is a growth factor for melanoma cells and a chemotaxin for neutrophils and a member of the CXC chemokine family that is a potent neutrophil attractant and activator and is also active toward basophils. CXCL1 is expressed by macrophages, neutrophils and epithelial cells; it has neutrophil chemoattractant activity. CXCL1 plays a critical nonredundant role in the development of experimental Lyme arthritis and carditis via CXCR2-mediated recruitment of neutrophils into the site of infection and may also have important pro-nociceptive effects via its direct actions on sensory neurons, and may induce long-term changes that involve protein synthesis.