Recombinant Human CXCL12(75AA)

Description

EnkiLife provides the Recombinant Human CXCL12(75AA) protein,aslo know as Stromal Cell-Derived Factor 1,SDF-1,hSDF-1,C-X-C Motif Chemokine 12,Intercrine Reduced in Hepatomas,IRH,hIRH,Pre-B Cell Growth-Stimulating Factor,PBSF,CXCL12,SDF1,SDF1A,SDF1B, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human C-X-C Motif Chemokine 12 is produced by our E.coli expression system and the target gene encoding Ser19-Met93 is expressed.Accession:P48061. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:8.79 KDa. Background:Stromal Cell-Derived Factor-1 (SDF-1) is a chemokine member of the intercrine family. SDF1 is expressed as five isoforms that differ only in the C terminal tail. SDF1α and SDF1β are identical except for the four residues present in the C-terminus of SDF1β but absent from SDF1α. SDF1 isoforms interact with CXCR4 and CXCR7 receptors on the cell surface, and can also bind syndecan4. SDF1 is known to influence lymphopoiesis, regulate patterning and cell number of neural progenitors, and promote angiogenesis. It also enhances the survival of myeloid progenitor cells.