Recombinant Human CXCL14 (BRAK) (E. coli)

Description

Chemokine CXC motif ligand 14, also known as breast and kidney-expressed chemokine BRAK , is a CXC chemokine that is a potent chemoattractant for neutrophils but not for T-cells, B-cells, monocytes or granulocytes. Mature CXCL14 has many conserved features of the CXC family and is 30 % homologous to the MIP-alpha and MIP-beta sequences, but differs in that it has an additional five amino acid sequence in between the third and fourth cysteines and a short N-terminus. It is usually highly expressed near its fibroblast source and in epidermal fibroblasts and keratinocytes of skin, but is absent from cancer cells.