Recombinant Human Dectin-1 (N-Fc)

Description

EnkiLife provides the Recombinant Human Dectin-1 (N-Fc) protein,aslo know as Beta-glucan receptor,BGR,CD369,CLEC7A,CLECSF12,CLECSF12DC-associated C-type lectin 1;Dectin1,Dectin-1,DECTIN1CANDF4, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human C-type Lectin Domain Family 7 Member A is produced by our Mammalian expression system and the target gene encoding Thr66-Met247 is expressed with a human IgG1 Fc tag at the N-terminus.Accession:Q9BXN2. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:46.9 KDa. Background:Dectin-1 was recently identified as the most important receptor for beta-glucan. It is a type II transmembrane protein which binds beta-1,3 and beta-1,6 glucans, and is expressed on most cells of the innate immune system and has been implicated in phagocytosis as well as killing of fungi by macrophages, neutrophils and dendritic cells. Recognition of beta-glucan by dectin-1 triggers effective immune response, including phagocytosis and proinflammatory factor production, to eliminate infecting fungi, which especially benefits immunocompromised patients against opportunistic fungal infection.