Recombinant Human DMP-1 (C-6His)

Description

EnkiLife provides the Recombinant Human DMP-1 (C-6His) protein,aslo know as Dentin Matrix Acidic Phosphoprotein 1,DMP-1,Dentin Matrix Protein 1,DMP1, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Dentin Matrix Protein 1 is produced by our Mammalian expression system and the target gene encoding Leu17-Tyr513 is expressed with a 6His tag at the C-terminus.Accession:Q13316. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:55 KDa. Background:May have a dual function during osteoblast differentiation. In the nucleus of undifferentiated osteoblasts, unphosphorylated form acts as a transcriptional component for activation of osteoblast-specific genes like osteocalcin. During the osteoblast to osteocyte transition phase it is phosphorylated and exported into the extracellular matrix, where it regulates nucleation of hydroxyapatite.