Recombinant Human DPT (C-Fc-6His)

Description

EnkiLife provides the Recombinant Human DPT (C-Fc-6His) protein,aslo know as Dermatopontin,Tyrosine-rich acidic matrix protein,TRAMP and DPT, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Dermatopontin is produced by our Mammalian expression system and the target gene encoding Gln19-Val201 is expressed with a human IgG1 Fc, 6His tag at the C-terminus.Accession:Q07507. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:49.9 KDa. Background:Dermatopontin, also known as Tyrosine-rich acidic matrix protein, TRAMP and DPT, is a secreted protein which belongs to the dermatopontin family. DPT is expressed in various tissues, such as fibroblasts, heart, skeletal muscle, brain and pancreas. It seems to mediate adhesion by cell surface integrin binding. DPT may serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment. DPT can enhance TGFB1 activity through interaction with decorin. In addition, DPT accelerates collagen fibril formation, stabilizes collagen fibrils against low-temperature dissociation and inhibits cell proliferation.