Recombinant Human EFNB2 (C-6His)

Description

EnkiLife provides the Recombinant Human EFNB2 (C-6His) protein,aslo know as Ephrin-B2,EPH-Related Receptor Tyrosine Kinase Ligand 5,LERK-5,HTK Ligand,HTK-L,EFNB2,EPLG5,HTKL,LERK5, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Ephrin-B2 is produced by our Mammalian expression system and the target gene encoding Ile28-Ala229 is expressed with a 6His tag at the C-terminus.Accession:P52799. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:23.24 KDa. Background:Ephrin-B2 is a type I transmembrane protein and belongs the Ephrin family. It binds to the receptor tyrosine kinases, such as EPHA4, EPHB4 and EPHA3. Ephrin-B2 has been implicated in mediating developmental events, especially in the nervous system, erythropoiesis and tumour metastasis. Ligation of Ephrin-B2 with complementary EphB receptors on adjacent cells results in a combination of forward (EphB receptors) and reverse (Ephrin-B2) signalling, which is central to tissue development and remodelling functions. In addition, Ephrin-B2 may play a role in constraining the orientation of longitudinally projecting axons.