Recombinant Human EMMPRIN (C-6His)

Description

EnkiLife provides the Recombinant Human EMMPRIN (C-6His) protein,aslo know as Basigin,5F7,Collagenase Stimulatory Factor,Extracellular Matrix Metalloproteinase Inducer,EMMPRIN,Leukocyte Activation Antigen M6,OK Blood Group Antigen,Tumor Cell-Derived Collagenase Stimulatory Factor,TCSF,CD147,BSG, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Extracellular Matrix Metalloproteinase Inducer is produced by our Mammalian expression system and the target gene encoding Ala22-His205 is expressed with a 6His tag at the C-terminus.Accession:P35613-2. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:21.16 KDa. Background:Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) belongs to the immunoglobulin superfamily, which has the homology to both the immunoglobulin V domain and MHC class II antigen β-chain. EMMPRIN is a transmembrane glycoprotein with different forms, resulting from different modes of glycosylation and N-terminal sequence variants. EMMPRIN can be expressed in breast cancer, oral squamous cell carcinoma, glioma, lymphoma, lung, bladder, and melanoma carcinomas cells. EMMPRIN promotes invasion, metastasis, growth, and survival of malignants cells, serves as a receptor for extracellular cyclophilinthe, may play a role in signal transduction.