Recombinant Human EphB1 (C-Fc)

Description

EnkiLife provides the Recombinant Human EphB1 (C-Fc) protein,aslo know as Ephrin Type-B Receptor 1,ELK,EPH Tyrosine Kinase 2,EPH-Like Kinase 6,EK6,hEK6,Neuronally-Expressed EPH,Related Tyrosine Kinase,NET,Tyrosine-Protein Kinase Receptor EPH-2,EPHB1,ELK,EPHT2,HEK6, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Ephrin Type-B Receptor 1 is produced by our Mammalian expression system and the target gene encoding Met18-Pro540 is expressed with a human IgG1 Fc tag at the C-terminus.Accession:P54762. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:85.6 KDa. Background:Ephrin Type-B Receptor 1 (EPHB1) is a single-pass type I membrane protein that belongs to the Ephrin-B family of receptor tyrosine kinases that is involved in embryonic nervous and vascular system development. EPHB1/EPHT2 contains two fibronectin type-III domains, one protein kinase domain and one SAM (sterile α motif) domain. EPHB1 could stimulate fibroblast motility on extracellular matrix in a kinase-dependent manner, which also correlated with its association with Grb7, an adaptor molecule implicated in the regulation of cell migration. It binds to ephrin-B1, ephrin-B2 and ephrin-B3. EPHB1 plays an important roles in diverse biological processes including nervous system development, angiogenesis, and neural synapsis formation and maturation and may be involved in cell-cell interactions in the nervous system.