Recombinant Human Ephrin-A1 (C-6His)

Description

EnkiLife provides the Recombinant Human Ephrin-A1 (C-6His) protein,aslo know as Ephrin-A1,EPH-Related Receptor Tyrosine Kinase Ligand 1,LERK-1,Immediate Early Response Protein B61,Tumor Necrosis Factor Alpha-Induced Protein 4,TNF Alpha-Induced Protein 4,EFNA1,EPLG1,LERK1,TNFAIP4, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Ephrin-A1 is produced by our Mammalian expression system and the target gene encoding Asp19-Ser182 is expressed with a 6His tag at the C-terminus.Accession:AAH32698.1. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:20.39 KDa. Background:Ephrin-A1 is a member of the A-type ephrin family of cell surface proteins that function as ligands for the A-type Eph receptor tyrosine kinase family. Ephrin-A1 can be induced by TNF and IL1B. Its expression levels can be down-regulated in primary glioma tissues compared to the normal tissues. The soluble monomeric form is expressed in the glioblastoma multiforme (GBM) and breast cancer cells. Soluble Ephrin-A1 is necessary for the transformation of HeLa and SK-BR3 cells and participates in the relocalization of EPHA2 away from sites of cell-cell contact during transformation. Ephrin-A1 plays an important role in angiogenesis and tumor neovascularization.