Recombinant Human ERp44 (C-6His)

Description

EnkiLife provides the Recombinant Human ERp44 (C-6His) protein,aslo know as Thioredoxin domain-containing protein 4,ER protein 44,KIAA0573,TXNDC4, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human ER Resident Protein 44 is produced by our Mammalian expression system and the target gene encoding Glu30-Asp402 is expressed with a 6His tag at the C-terminus.Accession:Q9BS26. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:44.2 KDa. Background:Endoplasmic reticulum resident protein 44 (TXNDC4) is is a 406 amino acid protein that contains one thioredoxin domain. TXNDC4 mediates thiol-dependent retention in the early secretory pathway and forms mixed disulfides with substrate proteins through its conserved CRFS motif.It can inhibit the calcium channel activity of ITPR1.It may have a role in the control of oxidative protein folding in the endoplasmic reticulum.