Recombinant Human FABP6 (N-6His)

Description

EnkiLife provides the Recombinant Human FABP6 (N-6His) protein,aslo know as Gastrotropin,GT,Fatty Acid-Binding Protein 6,Ileal Lipid-Binding Protein,ILBP,Intestinal 15 kDa Protein,I-15P,Intestinal Bile Acid-Binding Protein,I-BABP,FABP6,ILBP,ILLBP, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Fatty Acid-Binding Protein 6 is produced by our E.coli expression system and the target gene encoding Met1-Ala128 is expressed with a 6His tag at the N-terminus.Accession:AAH22489.1. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:16.6 KDa. Background:Fatty Acid-Binding Protein 6 (FABP6) is cytoplasmic protein that binds long-chain fatty acids and other hydrophobic ligands which belongs to the calycin superfamily. FABP6 expression is restricted in the small intestine to the ileum where it is involved in the enterohepatic circulation of bile acids. FABP6 forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior. Isoform 2 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa (at protein level). Isoform 1 is expressed in the jejunum, ileum, cecum and ascending colon intestine. FABP6 plays a role in fatty acid uptake, transport, and metabolism. FABP6 stimulates gastric acid and pepsinogen secretion. It seems to be able to bind to bile salts and bilirubins.