Recombinant Human Fas Ligand (N-6His)

Description

EnkiLife provides the Recombinant Human Fas Ligand (N-6His) protein,aslo know as apoptosis (APO-1) antigen ligand 1,Apoptosis antigen ligand,APT1LG1CD95L,APTL,CD178 antigen,CD178,CD95L,CD95-L,Fas antigen ligand,Fas ligand (TNF superfamily, member 6),Fas Ligand,FASLCD95 ligand,FASLG,TNFSF6, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Tumor Necrosis Factor Ligand Superfamily Member 6 is produced by our Mammalian expression system and the target gene encoding Pro134-Leu281 is expressed with a 6His tag at the N-terminus.Accession:P48023. Expression Host:Human Cells.Species:Human .Predicted Molecular Mass:17.7 KDa. Background:Fas ligand is also known as FasL, CD178, CD95L, or TNFSF6, is a homotrimeric type-II transmembrane protein that belongs to the tumor necrosis factor (TNF) family. Its ability to induce apoptosis in target cells plays an important role in the development, homeostasis, and function of the immune system. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.