Recombinant Human FBPase1 (C-6His,E. coli)

Description

EnkiLife provides the Recombinant Human FBPase1 (C-6His,E. coli) protein,aslo know as Fructose-1,6-Bisphosphatase 1,FBPase 1,D-Fructose-1,6-Bisphosphate 1-Phosphohydrolase 1,FBP1,FBP, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Fructose-1,6-Bisphosphatase 1 is produced by our E.coli expression system and the target gene encoding Ala2-Gln338 is expressed with a 6His tag at the C-terminus.Accession:P09467. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:37.89 KDa. Background:Fructose-1,6-Bisphosphatase 1 (FBPase 1) is a member of the FBPase class 1 family. FBPase 1 is a gluconeogenesis regulatory protein, which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. FBPase 1 can assume an active R-state, or an inactive T-state. FBPase 1 deficiency is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis in newborn infants or young children. FBPase 1 coupled with phosphofructokinase (PFK) is involved in the metabolism of pancreatic islet cells.