Recombinant Human FIS1 (C-6His)

Description

EnkiLife provides the Recombinant Human FIS1 (C-6His) protein,aslo know as Mitochondrial Fission 1 Protein,FIS1 Homolog,hFis1,Tetratricopeptide Repeat Protein 11,TPR Repeat Protein 11,FIS1,TTC11,CGI-135, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Mitochondrial Fission 1 Protein is produced by our E.coli expression system and the target gene encoding Met1-Gly122 is expressed with a 6His tag at the C-terminus.Accession:Q9Y3D6. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:15.3 KDa. Background:Mitochondrial Fission 1 Protein (FIS1) is a member of the FIS1 family. FIS1 is a single-pass membrane protein and contains one TPR repeat. FIS1 is part of the mitochondrial complex that promotes mitochondrial fission. FIS1 can induce cytochrome C discharge from the mitochondrion to the cytosol, eventually leading to apoptosis. In addition, FIS1 participates in peroxisomal growth and division. The C-terminus of FIS1 is required for mitochondrial or peroxisomal localization, while the N-terminus is necessary for mitochondrial or peroxisomal fission, localization and regulation of the interaction with DNM1L.