Recombinant Human FKBP4 (C-6His)

Description

EnkiLife provides the Recombinant Human FKBP4 (C-6His) protein,aslo know as Peptidyl-prolyl cis-trans isomerase FKBP4,51kDa FK506-binding protein,51kDa FK506-binding protein,59kDa immunophilin,FK506-binding protein 4,FKBP59,HSP-binding immunophilin,immunophilin FKBP52,Rotamase,FKBP4, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human 52 kDa FK506 Binding Protein is produced by our E.coli expression system and the target gene encoding Met1-Ala459 is expressed with a 6His tag at the C-terminus.Accession:Q02790. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:52.8 KDa. Background:FKBP4 act as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. FKBP4 may play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments, it also may have a protective role against oxidative stress in mitochondria. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening.