Recombinant Human FLT-3L

Description

EnkiLife provides the Recombinant Human FLT-3L protein,aslo know as Fms-Felated Tyrosine Kinase 3 Ligand, Flt3 Ligand, Flt3L, SL Cytokine, FLT3LG, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:≤10 EU/mg;Construction:Recombinant Human FLT-3L is produced by our Mammalian cell expression system and the target gene encoding Thr27-Pro184 is expressed.Accession:P49771. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:17.8 kDa. Background:Fms-Related Tyrosine Kinase 3 Ligand (FLT3LG) is a hematopoietic four helical bundle cytokine. Mature human Flt‑3 Ligand consists of a extracellular domain (ECD) with a cytokine-like domain and a juxtamembrane tether region, a transmembrane segment, and a cytoplasmic tail. Human and mouse Flt‑3 Ligand show cross-species activity. Flt‑3 Ligand is expressed as a noncovalently-linked dimer by T cells and bone marrow and thymic fibroblasts.It is structurally homologous to stem cell factor (SCF) and colony stimulating facor 1 (CSF-1). In synergy with other growth factors, Flt3 ligand stimulates the proliferation and differentiation of various blood cell progenitors by activiation of Flt 3 receptor.