Recombinant Human FSH (C-Flag,C-6His)

Description

EnkiLife provides the Recombinant Human FSH (C-Flag,C-6His) protein,aslo know as Follicle-stimulating hormone,FSH,FSH alpha/beta, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Follicle-Stimulating Hormone is produced by our Mammalian expression system and the target gene encoding Ala25-Ser116&Asn19-Glu129 is expressed with a Flag tag&6His at the C-terminus.Accession:P01215&P01225. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:11.5&13.5 KDa. Background:Human Follicle-stimulating hormone (FSH) is a member of glycoprotein hormones subunit beta family, whichalso includes LH, chorionic gonadotropin (CG) and thyroid-stimulating hormone (TSH). FSH and its familymembers are heterodimers consisting of non-covalently linked α- and β-subunits. They share an identical αsubunit, and β-subunits vary. FSH has a unique β-subunit (FSHβ), which confers its specific biologic activityand is responsible for interaction with the FSH-receptor which belongs to a subfamily of GPCRs calledleucine-rich-repeat-containing GPCRs (LGRs). FSH is secreted from the pituitary gland and regulatesreproduction in mammals. FSH stimulates sertoli cell proliferation in testes and supports spermatogenesis inmales, and induces the maturation of ovarian follicles in females.