Recombinant Human Galectin-9 (N-GST)

Description

EnkiLife provides the Recombinant Human Galectin-9 (N-GST) protein,aslo know as Galectin-9,Gal-9,Ecalectin,Tumor antigen HOM-HD-21,LGALS9,Gal-9delta5, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Galectin-9 is produced by our E.coli expression system and the target gene encoding Met1-Thr323 is expressed with a GST tag at the N-terminus.Accession:O00182-2. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:62.2 KDa. Background:Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkins disease tissue. Galectin-9 binds galactosides and has high affinity for the Forssman pentasaccharide. Galectin-9 plays a role in thymocyte-epithelial interactions relevant to the biology of the thymus and Inhibits cell proliferation. Galectin-9 is a ligand for HAVCR2/TIM3 and induces T-helper type 1 lymphocyte (Th1) death. In addition, Galectin-9 suppresses tumor cell metastasis by interfering with the associations CD44, VCAM-1, Integrin α4β1