GENERAL CATALOGUE
Recombinant Human GDNF (E. coli)
Z101059 · 10 ug 50 ug 1.0 mg
abm good · Cat: Z101059
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Catalog No: Z101059
Category: Cellular Materials
Pack Size: 10 ug 50 ug 1.0 mg
Brand: abm good
Description
GDNF is a disulfide-bonded homodimeric glycosylated protein of 134 amino acids. The amino acid sequences inferred from rat and human cDNAs are 93 % identical. The proteins contain seven conserved cysteine residues in the same relative spacing found in all members of the TGF-beta superfamily of proteins. In embryonic midbrain cultures GDNF promotes the survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.
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