Recombinant Human GMPR (C-6His)

Description

EnkiLife provides the Recombinant Human GMPR (C-6His) protein,aslo know as GMP Reductase 1,Guanosine 5-Monophosphate Oxidoreductase 1,Guanosine Monophosphate Reductase 1,GMPR,GMPR1, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human GMP Reductase 1 is produced by our Mammalian expression system and the target gene encoding Met1-Ser345 is expressed with a 6His tag at the C-terminus.Accession:AAH08281.1. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:38.5 KDa. Background:GMP Reductase 1 (GMPR) is a member of the IMPDH/GMPR family. GMPR exists as a homotetramer and catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. GMP reductase gene expression may be regulated by MITF. At least two different alleles are known.